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The Transcriptional Targets of Mutant FOXL2 in Granulosa Cell Tumours

BACKGROUND: Despite their distinct biology, granulosa cell tumours (GCTs) are treated the same as other ovarian tumours. Intriguingly, a recurring somatic mutation in the transcription factor Forkhead Box L2 (FOXL2) 402C>G has been found in nearly all GCTs examined. This investigation aims to ide...

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Detalhes bibliográficos
Main Authors: Rosario, Roseanne, Araki, Hiromitsu, Print, Cristin G., Shelling, Andrew N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460904/
https://ncbi.nlm.nih.gov/pubmed/23029457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046270
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