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Effects of Dopamine D(2) Receptor Partial Agonist Antipsychotic Aripiprazole on Dopamine Synthesis in Human Brain Measured by PET with L-[β-(11)C]DOPA

Dopamine D(2) receptor partial agonist antipsychotic drugs can modulate dopaminergic neurotransmission as functional agonists or functional antagonists. The effects of antipsychotics on presynaptic dopaminergic functions, such as dopamine synthesis capacity, might also be related to their therapeuti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ito, Hiroshi, Takano, Harumasa, Arakawa, Ryosuke, Takahashi, Hidehiko, Kodaka, Fumitoshi, Takahata, Keisuke, Nogami, Tsuyoshi, Suzuki, Masayuki, Suhara, Tetsuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460902/
https://ncbi.nlm.nih.gov/pubmed/23029533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046488
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