Measurement error analysis for the determination of dopamine D(2) receptor occupancy using the agonist radioligand [(11)C]MNPA

The purpose of this study is to investigate errors in quantitative analysis for estimating dopamine D(2) receptor occupancy of antipsychotics with agonist radioligand [(11)C]MNPA by numerical simulation, with particular attention to the validity of a quantitative approach based on the use of a refer...

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Detalhes bibliográficos
Main Authors: Shidahara, Miho, Ito, Hiroshi, Otsuka, Tatsui, Ikoma, Yoko, Arakawa, Ryosuke, Kodaka, Fumitoshi, Seki, Chie, Takano, Harumasa, Takahashi, Hidehiko, Turkheimer, Federico E, Kimura, Yuichi, Kanno, Iwao, Suhara, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949103/
https://ncbi.nlm.nih.gov/pubmed/19756020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.193
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