Effects of Dopamine D(2) Receptor Partial Agonist Antipsychotic Aripiprazole on Dopamine Synthesis in Human Brain Measured by PET with L-[β-(11)C]DOPA

Dopamine D(2) receptor partial agonist antipsychotic drugs can modulate dopaminergic neurotransmission as functional agonists or functional antagonists. The effects of antipsychotics on presynaptic dopaminergic functions, such as dopamine synthesis capacity, might also be related to their therapeuti...

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Autors principals: Ito, Hiroshi, Takano, Harumasa, Arakawa, Ryosuke, Takahashi, Hidehiko, Kodaka, Fumitoshi, Takahata, Keisuke, Nogami, Tsuyoshi, Suzuki, Masayuki, Suhara, Tetsuya
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460902/
https://ncbi.nlm.nih.gov/pubmed/23029533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046488
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