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Endothelin-1 Augments Na(+)/H(+) Exchange Activity in Murine Pulmonary Arterial Smooth Muscle Cells via Rho Kinase
Excessive production of endothelin-1 (ET-1), a potent vasoconstrictor, occurs with several forms of pulmonary hypertension. In addition to modulating vasomotor tone, ET-1 can potentiate pulmonary arterial smooth muscle cell (PASMC) growth and migration, both of which contribute to the vascular remod...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460862/ https://ncbi.nlm.nih.gov/pubmed/23029469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046303 |
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