Role of Rho kinase and Na(+)/H(+) exchange in hypoxia‐induced pulmonary arterial smooth muscle cell proliferation and migration

Abnormal proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) are hallmark characteristics of vascular remodeling in pulmonary hypertension induced by chronic hypoxia. In this study, we investigated the role of the Na(+)/H(+) exchanger (NHE) and alterations in intracellular...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Walker, Jasmine, Undem, Clark, Yun, Xin, Lade, Julie, Jiang, Haiyang, Shimoda, Larissa A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814889/
https://ncbi.nlm.nih.gov/pubmed/27009277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12702
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