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Rho kinase and Na(+)/H(+) exchanger mediate endothelin‐1‐induced pulmonary arterial smooth muscle cell proliferation and migration
Excessive production of endothelin‐1 (ET‐1) has been observed in almost all forms of pulmonary hypertension. ET‐1, a highly potent vasoconstrictor, can also potentiate pulmonary arterial smooth muscle cell (PASMC) growth and migration, both of which contribute to the vascular remodeling that occurs...
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| Udgivet i: | Physiol Rep |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5949284/ https://ncbi.nlm.nih.gov/pubmed/29756391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13698 |
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