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Expression and Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein in Saccharomyces cerevisiae

The cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel, that when mutated, can give rise to cystic fibrosis in humans.There is therefore considerable interest in this protein, but efforts to study its structure and activity have been hampered by the difficulty of expres...

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Bibliografiske detaljer
Main Authors: O'Ryan, Liam, Rimington, Tracy, Cant, Natasha, Ford, Robert C.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460588/
https://ncbi.nlm.nih.gov/pubmed/22433465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3860
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