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Ultrashort and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution
RNA synthesis and decay rates determine the steady-state levels of cellular RNAs. Metabolic tagging of newly transcribed RNA by 4-thiouridine (4sU) can reveal the relative contributions of RNA synthesis and decay rates. The kinetics of RNA processing, however, had so far remained unresolved. Here, w...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460197/ https://ncbi.nlm.nih.gov/pubmed/22539649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.131847.111 |
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