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Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations
X chromosome inactivation (XCI) achieves dosage balance in mammals by repressing one of two X chromosomes in females. During XCI, the long noncoding Xist RNA and Polycomb proteins spread along the inactive X (Xi) to initiate chromosome-wide silencing. Although inactivation is known to commence at th...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460182/ https://ncbi.nlm.nih.gov/pubmed/22948768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.133751.111 |
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