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Denatured G-Protein Coupled Receptors as Immunogens to Generate Highly Specific Antibodies

G-protein coupled receptors (GPCRs) play a major role in a number of physiological and pathological processes. Thus, GPCRs have become the most frequent targets for development of new therapeutic drugs. In this context, the availability of highly specific antibodies may be decisive to obtain reliabl...

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Autors principals: Talmont, Franck, Moulédous, Lionel, Boué, Jérôme, Mollereau, Catherine, Dietrich, Gilles
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459905/
https://ncbi.nlm.nih.gov/pubmed/23029489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046348
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