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Generation of G protein-coupled receptor antibodies differentially sensitive to conformational states

The N-terminal region of G protein-coupled receptors can be efficiently targeted for the generation of receptor-selective antibodies. These antibodies are useful for the biochemical characterization of the receptors. In this study, we developed a set of criteria to select the optimal epitope and app...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Heimann, Andrea S., Gupta, Achla, Gomes, Ivone, Rayees, Rahman, Schlessinger, Avner, Ferro, Emer S., Unterwald, Ellen M., Devi, Lakshmi A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665533/
https://ncbi.nlm.nih.gov/pubmed/29091950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187306
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