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Denatured G-Protein Coupled Receptors as Immunogens to Generate Highly Specific Antibodies

G-protein coupled receptors (GPCRs) play a major role in a number of physiological and pathological processes. Thus, GPCRs have become the most frequent targets for development of new therapeutic drugs. In this context, the availability of highly specific antibodies may be decisive to obtain reliabl...

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Detalhes bibliográficos
Main Authors: Talmont, Franck, Moulédous, Lionel, Boué, Jérôme, Mollereau, Catherine, Dietrich, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459905/
https://ncbi.nlm.nih.gov/pubmed/23029489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046348
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