Direct Binding of Occupied Urokinase Receptor (uPAR) to LDL Receptor-related Protein Is Required for Endocytosis of uPAR and Regulation of Cell Surface Urokinase Activity

Low-density lipoprotein receptor-related protein (LRP) mediates internalization of urokinase:plasminogen activator inhibitor complexes (uPA:PAI-1) and the urokinase receptor (uPAR). Here we investigated whether direct interaction between uPAR, a glycosyl-phosphatidylinositol–anchored protein, and LR...

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Veröffentlicht in:	Mol Biol Cell
Hauptverfasser:	Czekay, Ralf-Peter, Kuemmel, Thomas A., Orlando, Robert A., Farquhar, Marilyn Gist
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Cell Biology 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11359936/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.5.1467
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