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Direct Binding of Occupied Urokinase Receptor (uPAR) to LDL Receptor-related Protein Is Required for Endocytosis of uPAR and Regulation of Cell Surface Urokinase Activity

Low-density lipoprotein receptor-related protein (LRP) mediates internalization of urokinase:plasminogen activator inhibitor complexes (uPA:PAI-1) and the urokinase receptor (uPAR). Here we investigated whether direct interaction between uPAR, a glycosyl-phosphatidylinositol–anchored protein, and LR...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Czekay, Ralf-Peter, Kuemmel, Thomas A., Orlando, Robert A., Farquhar, Marilyn Gist
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Cell Biology 2001
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC34598/
https://ncbi.nlm.nih.gov/pubmed/11359936
תגים: הוספת תג
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