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Direct, Redox Neutral Prenylation and Geranylation of Secondary Carbinol C-H Bonds: C4 Regioselectivity in Ruthenium Catalyzed C-C Couplings of Dienes to α-Hydroxy Esters

The ruthenium catalyst generated in situ from Ru(3)(CO)(12) and tricyclohexylphosphine, PCy(3), promotes the redox-neutral C-C coupling of aryl substituted α-hydroxy esters to isoprene and myrcene at the diene C4-position, resulting in direct carbinol C-H prenylation and geranylation, respectively....

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Detalhes bibliográficos
Main Authors: Leung, Joyce C., Geary, Laina M., Chen, Te-Yu, Zbieg, Jason R., Krische, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459341/
https://ncbi.nlm.nih.gov/pubmed/22985393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3075049
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