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Fractional Proliferation: A method to deconvolve cell population dynamics from single-cell data
We present an integrated method that exploits extended time-lapse automated imaging to quantify dynamics of cell proliferation. Cell counts are fit with a Quiescence-Growth model that estimates rates of cell division, entry into quiescence and death. The model is constrained with rates extracted exp...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3459330/ https://ncbi.nlm.nih.gov/pubmed/22886092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2138 |
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