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The contribution of age structure to cell population responses to targeted therapeutics

Cells grown in culture act as a model system for analyzing the effects of anticancer compounds, which may affect cell behavior in a cell cycle position-dependent manner. Cell synchronization techniques have been generally employed to minimize the variation in cell cycle position. However, synchroniz...

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Detalhes bibliográficos
Main Authors: Gabriel, Pierre, Garbett, Shawn P., Quaranta, Vito, Tyson, Darren R., Webb, Glenn F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592383/
https://ncbi.nlm.nih.gov/pubmed/22796330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2012.07.001
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