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Adenosine Receptor Prodrugs: Synthesis and Biological Activity of Derivatives of Potent, A(1)-Selective Agonists
5′-Ester derivatives of the potent adenosine agonists N(6)-[4-[[[[4-[[[(2-acetylaminoethyl)amino] carbonyl] methyl] anilino] carbonyl] methyl] phenyl] adenosine (N-AcADAC; 1) and N(6)-cyclopentyladenosine (CPA; 2) were prepared as prodrugs. Both alkyl esters or carbonates (designed to enter the brai...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3459066/ https://ncbi.nlm.nih.gov/pubmed/8138909 |
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