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Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats

BACKGROUND: Recurrent/moderate (R/M) hypoglycemia is common in type 1 diabetes. Although mild or moderate hypoglycemia is not life-threatening, if recurrent, it may cause cognitive impairment. In the present study, we sought to determine whether R/M hypoglycemia leads to neuronal death, dendritic in...

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Detalhes bibliográficos
Main Authors: Won, Seok Joon, Yoo, Byung Hoon, Kauppinen, Tiina M, Choi, Bo Young, Kim, Jin Hee, Jang, Bong Geom, Lee, Min Woo, Sohn, Min, Liu, Jialing, Swanson, Raymond A, Suh, Sang Won
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458941/
https://ncbi.nlm.nih.gov/pubmed/22830525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-182
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