Pyruvate Administration Reduces Recurrent/Moderate Hypoglycemia-Induced Cortical Neuron Death in Diabetic Rats

Recurrent/moderate (R/M) hypoglycemia is common in type 1 diabetes patients. Moderate hypoglycemia is not life-threatening, but if experienced recurrently it may present several clinical complications. Activated PARP-1 consumes cytosolic NAD, and because NAD is required for glycolysis, hypoglycemia-...

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Detalhes bibliográficos
Main Authors: Choi, Bo Young, Kim, Jin Hee, Kim, Hyun Jung, Yoo, Jin Hyuk, Song, Hong Ki, Sohn, Min, Won, Seok Joon, Suh, Sang Won
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838412/
https://ncbi.nlm.nih.gov/pubmed/24278448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081523
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