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Synthesis of compounds related to the anti-migraine drug eletriptan hydrobromide
Eletriptan hydrobromide (1) is a selective serotonin (5-HT(1)) agonist, used for the acute treatment of the headache phase of migraine attacks. During the manufacture of eletriptan hydrobromide the formation of various impurities were observed and identified by LC–MS. To control the formation of the...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Beilstein-Institut
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458767/ https://ncbi.nlm.nih.gov/pubmed/23019477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.162 |
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