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Synthesis of compounds related to the anti-migraine drug eletriptan hydrobromide
Eletriptan hydrobromide (1) is a selective serotonin (5-HT(1)) agonist, used for the acute treatment of the headache phase of migraine attacks. During the manufacture of eletriptan hydrobromide the formation of various impurities were observed and identified by LC–MS. To control the formation of the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458767/ https://ncbi.nlm.nih.gov/pubmed/23019477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.162 |
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