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Synthesis of compounds related to the anti-migraine drug eletriptan hydrobromide
Eletriptan hydrobromide (1) is a selective serotonin (5-HT(1)) agonist, used for the acute treatment of the headache phase of migraine attacks. During the manufacture of eletriptan hydrobromide the formation of various impurities were observed and identified by LC–MS. To control the formation of the...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Beilstein-Institut
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458767/ https://ncbi.nlm.nih.gov/pubmed/23019477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.162 |
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