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Asymmetric one-pot sequential Friedel–Crafts-type alkylation and α-oxyamination catalyzed by a peptide and an enzyme

In the presence of a peptide catalyst and the oxidative enzyme laccase, a one-pot sequential reaction including a Friedel–Crafts-type alkylation of α,β-unsaturated aldehydes followed by an α-oxyamination was realized. The reaction in aqueous solvent to promote the enzymatic oxidation, and the use of...

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Détails bibliographiques
Auteurs principaux: Akagawa, Kengo, Umezawa, Ryota, Kudo, Kazuaki
Format: Artigo
Langue:Inglês
Publié: Beilstein-Institut 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458757/
https://ncbi.nlm.nih.gov/pubmed/23019467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.152
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