Lewis Acid-Catalyzed Enantioselective Friedel–Crafts Alkylation of Pyrrole in Water

[Image: see text] Highly enantioselective Friedel–Crafts alkylation of pyrroles with 2-enoyl-pyridine N-oxides in water/chloroform (10:1) was developed under catalysis of Lewis acid. The Friedel–Crafts alkylation products can be obtained in high yields and excellent enantioselectivities. Moreover, s...

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Опубликовано в: :ACS Omega
Главные авторы: Sun, Jianan, Gui, Yang, Huang, Yekai, Li, Jindong, Zha, Zhenggen, Yang, Yu, Wang, Zhiyong
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2020
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271029/
https://ncbi.nlm.nih.gov/pubmed/32548375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b04115
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