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Design of a novel tryptophan-rich membrane-active antimicrobial peptide from the membrane-proximal region of the HIV glycoprotein, gp41

A number of physicochemical characteristics have been described which contribute to the biological activity of antimicrobial peptides. This information was used to design a novel antimicrobial peptide sequence by using an intrinsically inactive membrane-associated peptide derived from the HIV glycop...

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Autors principals: Haney, Evan F, Nguyen, Leonard T, Schibli, David J, Vogel, Hans J
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458735/
https://ncbi.nlm.nih.gov/pubmed/23019445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.130
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