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Dissecting Heterogeneous Molecular Chaperone Complexes Using a Mass Spectrum Deconvolution Approach

Small Heat-Shock Proteins (sHSPs) are a family of molecular chaperones that help prevent irreversible aggregation through binding non-native target proteins to form large and heterogeneous complexes. These sHSP:target complexes are an integral part of the overall proteostasis network but, due to the...

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Autors principals: Stengel, Florian, Baldwin, Andrew J., Bush, Matthew F., Hilton, Gillian R., Lioe, Hadi, Basha, Eman, Jaya, Nomalie, Vierling, Elizabeth, Benesch, Justin L.P.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458707/
https://ncbi.nlm.nih.gov/pubmed/22633411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.04.007
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