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Substrate binding site flexibility of the small heat shock protein molecular chaperones
Small heat shock proteins (sHSPs) serve as a first line of defense against stress-induced cell damage by binding and maintaining denaturing proteins in a folding-competent state. In contrast to the well-defined substrate binding regions of ATP-dependent chaperones, interactions between sHSPs and sub...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773522/ https://ncbi.nlm.nih.gov/pubmed/19717454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902177106 |
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