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Inverted Alu dsRNA structures do not affect localization but can alter translation efficiency of human mRNAs independent of RNA editing

With over one million copies, Alu elements are the most abundant repetitive elements in the human genome. When transcribed, interaction between two Alus that are in opposite orientation gives rise to double-stranded RNA (dsRNA). Although the presence of dsRNA in the cell was previously thought to on...

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Detalhes bibliográficos
Principais autores: Capshew, Claire R., Dusenbury, Kristen L., Hundley, Heather A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458544/
https://ncbi.nlm.nih.gov/pubmed/22735697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks590
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