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Quantifying selection in high-throughput Immunoglobulin sequencing data sets
High-throughput immunoglobulin sequencing promises new insights into the somatic hypermutation and antigen-driven selection processes that underlie B-cell affinity maturation and adaptive immunity. The ability to estimate positive and negative selection from these sequence data has broad application...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458526/ https://ncbi.nlm.nih.gov/pubmed/22641856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks457 |
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