Rescue of Notch signaling in cells incapable of GDP-l-fucose synthesis by gap junction transfer of GDP-l-fucose in Drosophila

Notch (N) is a transmembrane receptor that mediates cell–cell interactions to determine many cell-fate decisions. N contains EGF-like repeats, many of which have an O-fucose glycan modification that regulates N-ligand binding. This modification requires GDP-l-fucose as a donor of fucose. The GDP-l-f...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Ayukawa, Tomonori, Matsumoto, Kenjiroo, Ishikawa, Hiroyuki O., Ishio, Akira, Yamakawa, Tomoko, Aoyama, Naoki, Suzuki, Takuya, Matsuno, Kenji
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458340/
https://ncbi.nlm.nih.gov/pubmed/22949680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202369109
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk