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Prostaglandin-stimulated GTP hydrolysis associated with activation of adenylate cyclase in human platelet membranes.
In membranes purified from human blood platelets, basal guanosine triphosphate (GTP) hydrolysis is reduced by a factor of approximately 6 by exposure to N-ethylmaleimide (10 mM). This decreased background enables the detection of an additional GTP hydrolysis in the presence of prostaglandin E1 (PGE1...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345823/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6121325/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.3.719 |
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