Salts promote activation of fat cell adenylate cyclase by GTP: special role for sodium ion.
The effects of GTP on adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] of human and rat fat cell membranes ("ghosts" and purified membranes) were examined in the absence and presence of added inorganic salts. With human ghosts GTP alone (0.1 mM) inhibited enzyme activity by 40% at...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1981
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349278/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6278472/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7417 |
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