Salts promote activation of fat cell adenylate cyclase by GTP: special role for sodium ion.

The effects of GTP on adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] of human and rat fat cell membranes ("ghosts" and purified membranes) were examined in the absence and presence of added inorganic salts. With human ghosts GTP alone (0.1 mM) inhibited enzyme activity by 40% at...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Katz, M S, Partilla, J S, Piñeyro, M A, Schneyer, C R, Gregerman, R I
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1981
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349278/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6278472/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7417
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