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Prostaglandin-stimulated GTP hydrolysis associated with activation of adenylate cyclase in human platelet membranes.

In membranes purified from human blood platelets, basal guanosine triphosphate (GTP) hydrolysis is reduced by a factor of approximately 6 by exposure to N-ethylmaleimide (10 mM). This decreased background enables the detection of an additional GTP hydrolysis in the presence of prostaglandin E1 (PGE1...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lester, H A, Steer, M L, Levitzki, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6121325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.3.719
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