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A Single-Day Treatment with Mifepristone Is Sufficient to Normalize Chronic Glucocorticoid Induced Suppression of Hippocampal Cell Proliferation

BACKGROUND: Chronic stress or prolonged administration of glucocorticoids suppresses proliferation and/or survival of newborn cells in adult rat dentate gyrus. Earlier we showed that administration of the glucocorticoid receptor antagonist mifepristone during the final 4 days of a 21 days period of...

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書誌詳細
主要な著者: Hu, Pu, Oomen, Charlotte, van Dam, Anne-Marie, Wester, Jordi, Zhou, Jiang-Ning, Joëls, Marian, Lucassen, Paul J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458013/
https://ncbi.nlm.nih.gov/pubmed/23049985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046224
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