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Hippocampal Proliferation Is Increased in Presymptomatic Parkinson's Disease and due to Microglia

Besides dopamine-deficiency related motor symptoms, nonmotor symptoms, including cognitive changes occur in Parkinson's disease (PD) patients, that may relate to accumulation of α-synuclein in the hippocampus (HC). This brain region also contains stem cells that can proliferate. This is a well-...

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Detalhes bibliográficos
Main Authors: Doorn, Karlijn J., Drukarch, Benjamin, van Dam, Anne-Marie, Lucassen, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147270/
https://ncbi.nlm.nih.gov/pubmed/25197578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/959154
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