Modulation of Toxin Production by the Flagellar Regulon in Clostridium difficile

We show in this study that toxin production in Clostridium difficile is altered in cells which can no longer form flagellar filaments. The impact of inactivation of fliC, CD0240, fliF, fliG, fliM, and flhB-fliR flagellar genes upon toxin levels in culture supernatants was assessed using cell-based c...

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Bibliografiske detaljer
Main Authors: Aubry, Annie, Hussack, Greg, Chen, Wangxue, KuoLee, Rhonda, Twine, Susan M., Fulton, Kelly M., Foote, Simon, Carrillo, Catherine D., Tanha, Jamshid, Logan, Susan M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457548/
https://ncbi.nlm.nih.gov/pubmed/22851750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00224-12
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