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The Combined Deletion of S6K1 and Akt2 Deteriorates Glycemic Control in a High-Fat Diet
Signaling downstream of mechanistic target of rapamycin complexes 1 and 2 (mTORC1 and mTORC2) controls specific and distinct aspects of insulin action and nutrient homeostasis in an interconnected and as yet unclear way. Mice lacking the mTORC1 substrate S6 kinase 1 (S6K1) maintain proper glycemic c...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457537/ https://ncbi.nlm.nih.gov/pubmed/22851690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00514-12 |
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