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The Combined Deletion of S6K1 and Akt2 Deteriorates Glycemic Control in a High-Fat Diet

Signaling downstream of mechanistic target of rapamycin complexes 1 and 2 (mTORC1 and mTORC2) controls specific and distinct aspects of insulin action and nutrient homeostasis in an interconnected and as yet unclear way. Mice lacking the mTORC1 substrate S6 kinase 1 (S6K1) maintain proper glycemic c...

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Detalhes bibliográficos
Main Authors: Treins, Caroline, Alliouachene, Samira, Hassouna, Rim, Xie, Yun, Birnbaum, Morris J., Pende, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457537/
https://ncbi.nlm.nih.gov/pubmed/22851690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00514-12
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