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Role of SUMOylation in Full Antiestrogenicity

The selective estrogen receptor downregulator (SERD) fulvestrant can be used as second-line treatment for patients relapsing after treatment with tamoxifen, a selective estrogen receptor modulator (SERM). Unlike tamoxifen, SERDs are devoid of partial agonist activity. While the full antiestrogenicit...

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Autors principals: Hilmi, Khalid, Hussein, Nader, Mendoza-Sanchez, Rodrigo, El-Ezzy, Mohamed, Ismail, Houssam, Durette, Chantal, Bail, Martine, Rozendaal, Maria Johanna, Bouvier, Michel, Thibault, Pierre, Gleason, James L., Mader, Sylvie
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457522/
https://ncbi.nlm.nih.gov/pubmed/22826433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00290-12
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