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Modeling Uncertainty in Single-Copy Assays for HIV

We present a simple computational model of measurement accuracy for single-copy sensitivity assays (SCA) of HIV RNA that was developed from first principles. The model shows that the SCA is significantly right-skewed. Measured virus concentrations of 1 and 10 virions/ml had overlapping 95% confidenc...

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Detalhes bibliográficos
Main Authors: Luo, Rutao, Piovoso, Michael J., Zurakowski, Ryan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457444/
https://ncbi.nlm.nih.gov/pubmed/22837324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01254-12
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