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Modeling-error robustness of a viral-load preconditioning strategy for HIV treatment switching

In previous work, we have developed optimal-control based approaches that seek to minimize the risk of subsequent virological failure by ”pre-conditioning” the viral load during therapy switches. In this paper, we use Monte-Carlo methods to evaluate the sensitivity of an open-loop implementation of...

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Autori principali: Luo, Rutao, Piovoso, Michael J., Zurakowski, Ryan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061758/
https://ncbi.nlm.nih.gov/pubmed/24954972
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