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Effect of Systemic Infection Induced by Pseudomonas aeruginosa on the Brain Uptake of Colistin in Mice

In view of reports of colistin-induced neurotoxicity in infected patients, the aim of this study was to assess whether the integrity of the blood-brain barrier (BBB) and the brain uptake of colistin are altered in the presence of systemic Pseudomonas aeruginosa infection. Bacteremia was confirmed 8...

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Autors principals: Jin, Liang, Li, Jian, Nation, Roger L., Nicolazzo, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457411/
https://ncbi.nlm.nih.gov/pubmed/22850514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00713-12
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