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Species-Dependent Blood-Brain Barrier Disruption of Lipopolysaccharide: Amelioration by Colistin In Vitro and In Vivo

The aim of this study was to use in vitro and in vivo models to assess the impact of lipopolysaccharide (LPS) from two different bacterial species on blood-brain barrier (BBB) integrity and brain uptake of colistin. Following repeated administration of LPS from Pseudomonas aeruginosa, the brain-to-p...

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Detalhes bibliográficos
Main Authors: Jin, Liang, Nation, Roger L., Li, Jian, Nicolazzo, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754325/
https://ncbi.nlm.nih.gov/pubmed/23796941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00765-13
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