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Colistin Methanesulfonate Is an Inactive Prodrug of Colistin against Pseudomonas aeruginosa

There is a dearth of information on the pharmacodynamics of “colistin,” despite its increasing use as a last line of defense for treatment of infections caused by multidrug-resistant gram-negative organisms. The antimicrobial activities of colistin and colistin methanesulfonate (CMS) were investigat...

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Main Authors: Bergen, Phillip J., Li, Jian, Rayner, Craig R., Nation, Roger L.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479097/
https://ncbi.nlm.nih.gov/pubmed/16723551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00035-06
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