Effect on Hepatitis C Virus Replication of Combinations of Direct-Acting Antivirals, Including NS5A Inhibitor Daclatasvir

Three hepatitis C virus (HCV) inhibitors, asunaprevir (ASV; BMS-650032), daclatasvir (DCV; BMS-790052), and BMS-791325, each targeting a different nonstructural protein of the virus (NS3, NS5A, and NS5B, respectively), have independently demonstrated encouraging preclinical profiles and are currentl...

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Bibliographic Details
Main Authors: Pelosi, Lenore A., Voss, Stacey, Liu, Mengping, Gao, Min, Lemm, Julie A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457360/
https://ncbi.nlm.nih.gov/pubmed/22850513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01209-12
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