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Synthesis of cholera toxin is positively regulated at the transcriptional level by toxR.

We have cloned a positive regulatory gene ( toxR ) from Vibrio cholerae that controls cholera toxin transcription. This was done by first constructing a genetic fusion consisting of the lacZ gene fused to the promoter of the cholera toxin operon ctxAB . This operon fusion was used to screen a V. cho...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Miller, V L, Mekalanos, J J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345530/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6374658/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.11.3471
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