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Synthesis of cholera toxin is positively regulated at the transcriptional level by toxR.

We have cloned a positive regulatory gene ( toxR ) from Vibrio cholerae that controls cholera toxin transcription. This was done by first constructing a genetic fusion consisting of the lacZ gene fused to the promoter of the cholera toxin operon ctxAB . This operon fusion was used to screen a V. cho...

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Bibliografske podrobnosti
Main Authors: Miller, V L, Mekalanos, J J
Format: Artigo
Jezik:Inglês
Izdano: 1984
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC345530/
https://ncbi.nlm.nih.gov/pubmed/6374658
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