Synthesis of cholera toxin is positively regulated at the transcriptional level by toxR.
We have cloned a positive regulatory gene ( toxR ) from Vibrio cholerae that controls cholera toxin transcription. This was done by first constructing a genetic fusion consisting of the lacZ gene fused to the promoter of the cholera toxin operon ctxAB . This operon fusion was used to screen a V. cho...
Salvato in:
| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1984
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345530/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6374658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.11.3471 |
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